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Why CRMs are Central to Method Development
Method development is a critical part of manufacturing pharmaceutical products and involves creating an analytical procedure used to evaluate the characteristics of a drug product against regulatory guidelines. The process includes several steps and, if implemented correctly, can ensure a successful drug product from discovery to market. The benefits of a successful analytical method include shorter turnaround times, cost savings, and accurate and reliable testing results. To ensure reliable analytical testing results, certified reference materials (CRMs) are of high importance as they provide a benchmark for accurate and comparable results in laboratories worldwide1. Additionally, CRMs are used for calibrating equipment and quality control applications. In this blog post, we look at wh...
Key Considerations for XRF Pelletising
Determining a material’s elemental composition requires instruments’ sensitivity and stability to achieve accurate results. Previously, those two factors were the most common source of error in XRF analysis, but as technology has advanced, so have the XRF instruments, which has meant they are no longer the primary source of error in an XRF sample analysis. Instead, the most common problems are found in sample preparation techniques. This blog post will look at the key considerations when using XRF pelletising as a preparation method.
What is XRF Pelletising?
Pelletising is the process of making pressed pellets for XRF analysis. Pressed pellets are a...
What Makes Ammonium Iodide an Ideal Release Agent?
Ammonium iodide is the scientific name of the chemical compound NH₄I. It is used in colour dyes, explosives, photographic chemicals, medications and fire extinguishers, and is created by combining ammonia and hydroiodic acid.
How to Prepare Samples for XRF Analysis
XRF analysis is a comparative chemical analysis technique that can precisely identify and quantify myriad different elements in samples. These are identified under an X-ray by using flux. Flux shows the intensity of an X-ray beam, as well as the number of photons that appear and the per unit time from the X-ray. The measurement for flux is defined as photons per second, also known as p.p.s.
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